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Palmitoylethanolamide (PEA): a well-tolerated dietary supplement with helpful anti-inflammatory & anti-depressive properties

I was intrigued to see the recent paper by Ghazizadeh-Hashemi et al - "Palmitoylethanolamide as adjunctive therapy in major depressive disorder: A double-blind, randomized and placebo-controlled trial" - with its abstract reading: "Experimental studies provide evidence for antidepressant effects of Palmitoylethanolamide (PEA) in animal models of depression.  We aimed to evaluate the efficacy and tolerability of PEA add-on therapy in treatment of patients with major depressive disorder (MDD).  Methods In a randomized double-blind, and placebo-controlled study, 58 patients with MDD (DSM-5) and Hamilton Depression Rating Scale (HAM-D) score ≥ 19 were randomized to receive either 600 mg twice daily Palmitoylethanolamide or placebo in addition to citalopram for six weeks ...

Twelve recent research studies on diet, psychological symptoms & wellbeing (2nd post): magnesium, zinc, folate, fish & selenium

I wrote a post a couple of days ago entitled "Twelve recent research studies on diet, psychological symptoms & wellbeing (1st post): overall dietary quality & depression".  I said that glancing back over recent research studies that I have noticed & downloaded to my personal database, I was struck by a whole series on the effects of diet on psychological state.  I've listed twelve that caught my eye in the last several months - the first post gave half a dozen on overall dietary quality & depression, whereas this post focuses more on specific dietary components.

Twelve recent research studies on diet, psychological symptoms & wellbeing (1st post): overall dietary quality & depression

Glancing back over recent research studies that I have noticed & downloaded to my personal database, I was struck by a whole series on the effects of diet on psychological state.  I've listed twelve that caught my eye in the last several months - this first of two posts details studies that focus more on overall dietary quality.  The second post in the series focuses more on specific dietary components & psychological disorder.  There are obviously lots of interesting developments in this important area.

M: Life skills for stress, health & wellbeing, session 12

“ I thank You God for most this amazing day: for the leaping greenly spirits of trees and a blue true dream of sky; and for everything which is natural which is infinite which is yes. ” - E E Cummings

Yesterday we had the twelfth & final session of this "Life skills" evening class.  There was scheduled to have been a bit less than a three month gap since the last - eleventh - session.  However the heavy winter snow we'd experienced had resulted in this last session being postponed.

L: Life skills for stress, health & wellbeing, session 11

Do not be too timid and squeamish about your actions. All life is an experiment. The more experiments you make the better. What if they are a little coarse and you may get your coat soiled or torn? What if you do fail, and get fairly rolled in the dirt once or twice? Up again, you shall never be so afraid of a tumble.

- Ralph Waldo Emerson
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