I was intrigued to see the recent paper by Ghazizadeh-Hashemi et al - "Palmitoylethanolamide as adjunctive therapy in major depressive disorder: A double-blind, randomized and placebo-controlled trial" - with its abstract reading: "Experimental studies provide evidence for antidepressant effects of Palmitoylethanolamide (PEA) in animal models of depression.  We aimed to evaluate the efficacy and tolerability of PEA add-on therapy in treatment of patients with major depressive disorder (MDD).  Methods In a randomized double-blind, and placebo-controlled study, 58 patients with MDD (DSM-5) and Hamilton Depression Rating Scale (HAM-D) score ≥ 19 were randomized to receive either 600 mg twice daily Palmitoylethanolamide or placebo in addition to citalopram for six weeks ...

I'm running a workshop today on "Biological treatments for psychological disorders: an overview & update for therapists".  You can download the 100 plus slides by clicking here.  The overall outline of the day is illustrated in this slide:

Last year I was intrigued by a paper - "Zinc in depression: A meta-analysis" - from Toronto University's "Neuropsychopharmacology Research Group" where the authors brought together 17 relevant studies and concluded "Depression is associated with a lower concentration of zinc in peripheral blood.

"The truth is rarely pure and never simple"   Oscar Wilde 

I wrote a post a couple of days ago entitled "Twelve recent research studies on diet, psychological symptoms & wellbeing (1st post): overall dietary quality & depression".  I said that glancing back over recent research studies that I have noticed & downloaded to my personal database, I was struck by a whole series on the effects of diet on psychological state.  I've listed twelve that caught my eye in the last several months - the first post gave half a dozen on overall dietary quality & depression, whereas this post focuses more on specific dietary components.

Glancing back over recent research studies that I have noticed & downloaded to my personal database, I was struck by a whole series on the effects of diet on psychological state.  I've listed twelve that caught my eye in the last several months - this first of two posts details studies that focus more on overall dietary quality.  The second post in the series focuses more on specific dietary components & psychological disorder.  There are obviously lots of interesting developments in this important area.

“

A human being is a part of the whole called by us universe, a part limited in time and space. He experiences himself, his thoughts and feeling as something separated from the rest, a kind of optical delusion of his consciousness. This delusion is a kind of prison for us, restricting us to our personal desires and to affection for a few persons nearest to us. Our task must be to free ourselves from this prison by widening our circle of compassion to embrace all living creatures and the whole of nature in its beauty.

” - Einstein

Yesterday we had the twelfth & final session of this "Life skills" evening class.  There was scheduled to have been a bit less than a three month gap since the last - eleventh - session.  However the heavy winter snow we'd experienced had resulted in this last session being postponed.

“ We must all die. But that I can save (a person) from days of torture, that is what I feel as my great and ever new privilege. Pain is a more terrible lord of mankind than even death himself. ” - Albert Schweitzer