Fish, fish oils, and n-3 fatty acids are often in the health news.  Here are seven recent papers illustrating the breadth of fish oil relevance.  The papers look at treatment of rheumatoid arthritis, the potential of flax as a dietary source of n-3 fatty acids, effects on indicators of cardiovascular disease, potential protection against dementia, reduction in mortality, and importance in pregnancy.  The papers also illustrate the patchwork, three steps forward/one step back, meandering, spreading, accretion of scientific knowledge.  As the proverb goes "One swallow doesn't make a summer".  Similarly, a single research study is usually simply one brick in the gradual building of our knowledge.  For more on fish and n-3 fatty acids, see other relevant blog posts I've written, articles in the linked Connotea database, and some recommended websites.     

This is the third in a series of blog posts on last Wednesday's SIGN draft guideline seminar on "Non-pharmacological management of mild to moderate depression."  The first session of the day was on "Lifestyle and Alternative/Complementary Therapies 1".  Yesterday's blog discussed the first presenter, Ian Ross's talk on the value of exercise in depression.  The second presentation was by Cliff Sharp, a psychiatrist from NHS borders.  He reviewed St John's Wort & Dietary Supplements.  He talked about the possible value of folate in treating depression when used to supplement conventional antidepressants.  He concluded that current evidence was insufficient to determine whether folate boosts response for those on antidepressants only if their initial folate levels are low, or whether it boosts response for anyone taking antidepressants.  See an

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A recent study in the British Journal of Nutrition (Rogers, Appleton et al. 2008) throws doubt on the value of fish oil supplementation as a treatment for depression. The authors stated " ...